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proline bronco body 25 × 10−13), indicating that a defective MA layer can still affect the diffusion of Env trimers despite the inability to incorporate Env into released particles (SI Appendix, Fig. Interestingly, a larger statistical difference is observed when comparing the mobility of Env Y712A with Env ∆CT trimers proximal to functional MA layers (P 1. 82 × 10−15), and a smaller reduction in mobility is observed when comparing Env Y712A proximal to the MA L12E lattice with Env ∆CT proximal to the MA WT lattice (P 6. These findings indicate that the Env CT dominantly drives the observed reduction in mobility at virus assembly sites when compared with a mutated MA layer. Error estimates from the distribution of Dapparent and SMSS values are SD, and P values were obtained using the Peacock method traxxas udr wheels and the 2D Kolmogorov–Smirnov test.

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